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Esta triple accin lo diferencia de predecesores como la semaglutida (solo GLP-1) y la tirzepatida (GLP-1 y GIP).(1) Al activar el receptor de glucagn, Retatrutide aade un componente nuevo: el aumento del gasto energtico y la quema de lpidos (termognesis), adems de la supresin del apetito y la mejora en la sensibilidad a la insulina proporcionada por los agonistas GLP-1 y GIP.(2) Los ensayos clnicos de fase 2 han mostrado resultados impresionantes
45 The vitamin D-folate hypothesis highlights a potential role for folate in preventing DNA damage through driving the evolution of skin pigmentation
Lifestyle as Medicine What Tuell and colleagues highlight is both reassuring and empowering: glutathione is not fixed
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A new wave of next-gen anti-obesity drugs is already in development, promising even greater efficacy and different mechanisms of action
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