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People with type 1 diabetes who need to lose weight can benefit from the blockbuster GLP-1 drug semaglutide currently approved only for type 2 diabetes, according to results from a small trial

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The interpretation of these findings is confounded by the low number of dementia cases in each study

Therefore, the aim of this review of published data is to compare the magnitude and duration of the effects on HR induced by various GLP-1 RAs, both in healthy individuals and in those with T2DM, utilizing individual 24-h HR measurements from clinical trials, including head-to-head comparison data

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