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Purpose-built for physicians GLP-1 receptor agonists may manage idiopathic intracranial hypertension Key takeaways: Patients with idiopathic intracranial hypertension can be managed medically
Gupta T, Kaur M, Shekhawat D, Aggarwal R, Nanda N, Sahni D (2023) Investigating the Glucagon-like Peptide-1 and its receptor in human brain: Distribution of expression, functional implications, age-related changes and species-specific characteristics
Beyond structural membrane functions, this pathway supports biosynthesis of coenzyme Q10 (CoQ10) and glutathione peroxidase 4 (GPX4), both of which contribute to suppression of lipid peroxidation [67]
32,35 Simultaneous exposure to diuretics, renin-angiotensin-aldosterone system inhibitors during hypovolaemia, non-steroidal anti-inflammatory medicines, contrast media, and other nephrotoxic agents may potentiate the risk of renal adverse events
Thyroid cancer Although only observed in animal studies, GLP-1-RAs can lead to thyroid C-cell hyperplasia and malignancies
