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GLP-1 GLP-1 12.5mg1INJE800021,1001123mg6RYBE350028,0275503[INJE8000]1,650/ 110,00030,000 GLP-1 GLP-1 GLP-1 12kg 9kg 2 1 GLP-1 GLP-1 3mg110,0006,0008,000 23kg GLP-1 GLP-1 10kg GLP-1 1 GLP-18 GLP-1 GLP-1 GLP-1 DMM elife / GLP-1 INJE8000 8,00019,115 1,650 GLP-1 GLP-1 *2.5mg1INJE800021,100// GLP-1 INJE8000 117,4002.5mg GLP-1 401 GLP-1 GLP-1 LINE 1 / GLP-1 LINE LINEURL GLP-1 LINE LINE LINE LINE DMMGLP-1 DMMGLP-1 DMM / GLP-1511 / elife elife 17 / 24365 24365 GLP-1 / / GLP-1 / GLP-1 GLP-1 310kg 710kp 120,00030,000 GLP-1 1 ?710kg 710kg GLP-1 123kg / * 3kg 3kg 10,000 / 5kg 5kg GLP-1 * 4.97.2kg GLP-1 4.97.2kg1kg Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study GLP-113 GLP-1 13 GLP-1 GLP-1 1 4,527 / GLP-1 GLP-1 GLP-1 /1,650 GLP-1 GLP-1 120,00026,000 / 141 GLP-1 GLP-1elife / GLP-1 1 GLP-1 GLP-1 GLP-1 3 GLP-1 GLP-1 10 40 20 GLP-1 28 GLP-1 GLP-1 BMI25 BMI272 GLP-1 GLP-1 GLP-1 GLP-11 GLP-1 BMI27BMI GLP-13 GLP-11 GLP-1 GLP-1 1 1 GLP-1 GLP-1 24 GLP-1 24 4 GLP-1 GLP-11 GLP-1 GLP-1 GLP-1 1 GLP-1 GLP-1 1GLP-1 2 GLP-1 GLP-17kg 3 GLP-1 120mL 30 GLP-1 GLP-1 GLP-1 GLP-1 GLP-1 GLP-1 GLP-1 GLP-1 GLP-1 GLP-1 12 21 GLP-1 AmazonECGLP-1 GLP-1 GLP-1 BMI18.5 BMIkgmm GLP-1 GLP-1 GLP-1 GLP-1 GLP-1 GLP-1 GLP-1 GLP-1 11 120ml GLP-1 11 1 GLP-1 GLP-1 GLP-1 GLP-1

The existing evidence base supports weekly injections as the optimal frequency for sustained weight loss, appetite suppression, and blood sugar control

The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus

Nature 409:307312