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More serious adverse effects are rare

Compounds binding there can stabilise the active conformation without needing to mimic the full peptide-extracellular-domain interaction

i) LASSS-treated HGF, at as low as 1 ng/ml that is below 2.510 ng/ml of the optimal final-concentration range in culture media (supplementary Figure 1a, left light-blue bar ), activates satellite cells to the maximum level presented by the positive control ( black bar PC , 5 ng/ml HGF)

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