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Most importantly, neither agent has raised major red flags in terms of serious adverse events in the trials conducted to date

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They then navigate across the endothelial layer either by traversing the TJs or by forming transient pores in the endothelium without compromising the structural integrity of complex TJs

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Assessment of trimethylamine-N-oxide at the blood-cerebrospinal fluid barrier: results from 290 lumbar punctures

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Where there is limited evidence, physicians are relying on their training and clinical knowledge to guide them

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