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Byetta, the first GLP-1 on the market in 2005, was used to treat diabetes, and other GLP-1s soon followed

Studies on MASLD have shown that arbutin can inhibit FTO activity to enhance the m 6 A methylation level of SLC7A11, stabilize its mRNA, and promote protein expression

Homma A, Sato H, Okamachi A, Emura T, Ishizawa T, Kato T, Matsuura T, Sato S, Tamura T, Higuchi Y, Watanabe T, Kitamura H, Asanuma K, Yamazaki T, Ikemi M, Kitagawa H, Morikawa T, Ikeya H, Maeda K, Takahashi K, Nohmi K, Izutani N, Kanda M, Suzuki R

Mall MA

Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease