In addition to being administered as a drug to cause oxidative stress, MTX has also been used to induce cachexia, anorexia, intestinal mucositis and digestive absorption problem in experimental animal models (Reference Boukhettala, Leblond and Claeyssens34Reference Sinno, Coquerel and Boukhettala36)
Furthermore, 84% of patients with pre-diabetes returned to normoglycemia, compared with 47.8% in placebo
The role of leptin in anorexia nervosa: clinical implications
Reach out promptly if you experience persistent or severe abdominal pain (especially radiating to the back), significant or persistent vomiting, signs of low blood sugar if you also take diabetes medications, a lump or swelling in your neck, hoarseness or difficulty swallowing, vision changes if you have a history of diabetic retinopathy, or signs of a serious allergic reaction
Hydrogen peroxide toxicity in human thyroid cells