Dry powder can tolerate brief periods at room temperature, up to several weeks, without catastrophic degradation
Reducing or skipping caffeine after regular use may cause: Headaches Fatigue Irritability Difficulty concentrating Low mood Daily GHOST Energy use deserves reconsideration when it is being used to hide: Chronic sleep deprivation Poor hydration Inadequate food intake Excessive training High stress Persistent unexplained fatigue More caffeine is not always the correct solution
In a retrospective cohort study including 7,044 patients with T2D, obesity (BMI 27 kg/m 2 ) and HFpEF, combination therapy with an SGLT2i and GLP-1 RA showed a lower risk of HF exacerbation, all-cause emergency department visits and new-onset kidney injury compared with patients only receiving SGLT2i
Jastreboff and colleagues (NEJM, 2023) reported substantial body-weight reduction in obesity research populations, and Rosenstock and colleagues (Lancet, 2023) documented glycemic and weight effects in type-2 diabetes research populations
Yatham LN, Schaffer A, Kessing LV, Miskowiak K, Kapczinski F, Vieta E, et al