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Growth hormone secretagogues and receptor selectivity

In a phase 2 clinical trial targeting obese individuals without type 2 diabetes (T2D), retatrutide dosed at 1 to 12 mg resulted in up to 24.2% weight loss over a 48-week treatment period, compared to 2.1% in the placebo group, and demonstrated a dose-dependent effect

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The Changing Treatment Paradigm Retatrutides arrival will likely shift how physicians and patients think about obesity treatment

However, as with any medical intervention, there are important contraindications to consider