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Whether patients progress in diabetic retinopathy or not, I would rather we potentially ameliorate their macrovascular risk of cardiovascular and cerebrovascular diseases, instead of worrying about microvascular, eye-related risks that we can manage appropriately with current modalities. New Indication, New Patients
Oral protocols are particularly suitable for gastrointestinal applications, where the direct contact between the peptide and gut tissue provides both systemic and local benefits
The Author(s) 2025
Medication is sold as 4- or 6-month prepaid supplies with no refund on unused months once medication has shipped
Abbreviations BMI: Body mass index CVOT: Cardiovascular outcomes trial EASD: European Association for the Study of Diabetes eGFR: Estimated glomerular filtration rate EUR: 2021 Euros GLP-1: Glucagon-like peptide-1 HbA1c: Glycated hemoglobin HDL: High-density lipoprotein ICER: Incremental cost-effectiveness ratio NHS: National Health Service NMA: Network meta-analysis OAD: Oral antidiabetic medication PSP: Pharmacy selling price QALY: Quality-adjusted life year SGLT-2: Sodium-glucose cotransporter-2 SMBG: Self-monitoring of blood glucose UKPDS: United Kingdom Prospective Diabetes Study VAT: Value-added tax WHO: World Health Organization References International Diabetes Foundation
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