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The 0.5 mg/mL inclusion is well below any clinical toxicity threshold and has no effect on tirzepatide's GIP or GLP-1 receptor binding
In severe cases this requires hospitalization and ventilatory support
The short plasma half-life (~14 minutes) means peak levels are transient, which is why weekly or biweekly protocols are common in clinical practice
Marques, Natlia Nunes, Bruno Paulo Rodrigues Lustosa, Daniel Wagner Castro Lima Santos, Flvio Queiroz-Telles, Sybren de Hoog, Renata R
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