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The low incidence of DVT after sclerotherapy (less than 1 per 10,000 sessions 38 ) is the ultimate evidence that thrombosis is an epiphenomenon of the sclerosing process, not a goal

patients with more adipose tissue at the injection site do not need a longer needle, since subcutaneous tissue is typically reached within the first few millimeters of insertion

Many people develop low vitamin B12 levels gradually

Third, gene therapy approaches face unresolved safety concerns, including off-target mutagenesis, immune responses against Cas9, and potential oncogenesis from integrating viral vectors [139]

But animals arent humans