Patients can expect mild and transient side effects on treatment initiation, including nausea, vomiting, constipation, diarrhea, and headaches
If you experience any severe reactions, such as difficulty breathing, severe nausea, or signs of an allergic reaction (rash, swelling), it is important to contact your healthcare provider immediately
A 2024 meta-analysis focusing on PCOS patients revealed that GLP-1 receptor agonists significantly lowered fasting insulin levels, improved results on the 2-hour postoral glucose tolerance test, and reduced HOMA-IR, a key marker of insulin resistance
You should not
New England Journal of Medicine (2025) The REDEFINE 1 Phase 3 trial was a landmark 68-week, double-blind, randomized study comparing CagriSema (cagrilintide 2.4 mg plus semaglutide 2.4 mg) with semaglutide alone, cagrilintide alone, and placebo in 3,417 adults with obesity or overweight without diabetes