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Yes, GLP-1 medications can affect menstrual cycles, primarily through rapid weight loss, appetite suppression, and indirect hormonal signaling
7,9 Although GLP1 RA-based therapies can play an important role in T2D and weight management, they should not be prescribed without a comprehensive lifestyle intervention
The pineal gland produces melatonin, the hormone that regulates sleep-wake cycles
On the other hand, it is still not entirely clear whether the hepatic effects of GLP-1 are direct or indirect, as recent studies have not clearly demonstrated the presence of GLP-1 receptors in human hepatocytes
Johnson JB, John S, Laub DR
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