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Doctors follow strict rules to make sure its done right and doesnt hurt too much
concerns regarding unpredictable absorption The mechanism for the oral route is based on passive absorption of vitamin B 12 (without binding to intrinsic factor) as well as active absorption (following binding to intrinsic factor, if present, e.g
[28] mhra.gov.uk or via the Yellow Card app), which helps monitor the safety of medicines and supplements in the UK
Notably, a recent study found that LAT1 was a pH-dependent but not pH-independent transporter, whose maximal transporter activity is at neutral pH but much lower at acidic pH (Cosco et al., 2020)
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