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Moran et al
Chronic oxidative stress in the brainstem and peripheral nerves keeps the autonomic nervous system locked in a state of sympathetic dominance (the "fight-or-flight" response)
Abnormal mitochondrial DNA copy number and mitochondrial gene mutations in patients with PCOS have been the focus of recent research, with mitochondrial dysfunction increasingly recognized as a contributing factor in PCOS [38]
Interest in DSIP research declined over time, partly because of mixed clinical findings and partly because peptide research funding shifted toward other compounds
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