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However, despite its broad substrate specificity, OCTN1 has relatively low transport efficiency for carnitine and plays a limited role in carnitine transport [168, 169]

Eur J Pharm Biopharm 158:336346 Gong S-J, Kim HR, Park Y-J, Kim J-E (2025) Recent trends in continuous manufacturing and digitalization in pharmaceutical process development and manufacturing

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In SURMOUNT-1 (NEJM 2022, 2,539 adults with obesity), the 15 mg arm averaged 22.5% body weight loss at 72 weeks, the 10 mg arm 21.4%, and the 5 mg arm 16.0%