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Sequencing libraries were generated using NEBNext UltraTM RNA Library Prep Kit for Illumina (NEB, USA) following manufacturers recommendations and index codes were added to attribute sequences to each sample

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Following are the common skin whitening treatments: Chemical Peels Laser Skin Whitening Glutathione Injections Microdermabrasion Each of these treatments works differently and thus has varied timelines for improving pores and skin lightening

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