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Glycine variants of both peptides cost more because the alternate buffer system requires more complex compounding

The absence of trial data on the combination means any interaction would have to be inferred from theory rather than evidence

21 GABA alleviates tic-like behaviors through multiple mechanisms, including restoring neurotransmitter balance, modulating the CSTC (cortico-striatal-thalamic-cortical) circuit, reducing neuronal hyperexcitability, interacting with the gut-brain axis, exerting anti-inflammatory effects, and mitigating stress and anxiety

Statistical significance was determined by Students t -test or using analysis of variance (ANOVA) with Tukey tests for post hoc comparisons at a 1% or 5% significance level of difference

Nash C, et al