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Initial assessment should include a detailed history characterizing the joint symptoms: onset relative to medication initiation, location and pattern of joint involvement, severity and functional impact, aggravating and relieving factors, and any associated symptoms such as swelling, redness, or morning stiffness
This mini-review integrates pharmacological, physiological, and nutritional perspectives to examine the mechanisms underlying GLP-1induced weight loss and the physiological limits of thermogenic pathways in humans
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