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An RCT in 72 patients with NAFLD found that NAC (600 mg twice daily) for 3 months significantly improved liver enzymes (ALT, AST) and markers of oxidative stress compared to control, though it did not significantly improve liver histology on biopsy (Khoshbaten et al., Hepat Mon, 2010) [33]
Additional mechanisms
& Strang, J
Research continues into optimizing dosing protocols for different patient populations, including those with specific metabolic conditions
Gastrointestinal side effects tend to be less at a lower dose so thats possible, says Levy who has done consulting work for Novo Nordisk
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