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Within 48 hours after injection of 100 or 1000 mcg of vitamin B 12, 50 to 98% of the injected dose may appear in the urine

For people with cobalt allergy (which is more common among people with nickel allergy) who are also at risk of vitamin B12 deficiency, the "general advice seems to be 'take just enough but not too much,' which isn't too different from dosing advice for all vitamins and drugs" (via ACSH)

Supporting Long-Term Wellness with Regular B12 Injections Regular B12 injections help maintain optimal B12 levels, preventing the recurrence of symptoms like fatigue, nerve damage, and cognitive decline

Inject TB-500 subcutaneously in the abdomen

[36] The MMACHC gene product catalyzes the decyanation of cyanocobalamin as well as the dealkylation of alkylcobalamins including methylcobalamin and adenosylcobalamin