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To bypass the skin barrier, several support techniques are being studied, such as: Microneedles: Tiny needles create microchannels in the skin, allowing drugs to enter the bloodstream directly
With proper training and guidance from healthcare professionals, it is possible to self-administer B12 injections
More recent DSIP and DSIP-analogue research, involving modified compounds designed to behave similarly to DSIP, has explored possible neuroprotective and stroke-recovery roles in animal models, but this work remains preclinical rather than validated through large human therapeutic trials [1112][1819]