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Yes, DSIP and melatonin work through different mechanisms

Kukla A, Hill J, Merzkani M, et al

Many preclinical studies have demonstrated that the expression of key enzymes for GSH synthesis (GCL, SLC7A11, GS) and GSSG reduction-related enzymes (G6PD, NADPH, and GR) is downregulated in myocardium exposed to pathological factors [40, 43,44,45,46,47,48,49,50]

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Consequently, research teams can develop repeatable procedures that support scientific consistency, organized documentation, and dependable analytical practices