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This is often the first sign the therapy is working

10.1056/NEJMra1804281 65 GaoC.JiS.DongW.QiY.SongW.CuiD.et al (2015)

Women who have seen dramatic before-and-after transformations on GLP-1 medications often describe a complete shift in how they experience their own bodies during intimacy

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Because starting doses are intentionally low, dramatic changes are not usually expected during the first several weeks