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The model predicts that initial knock-down of Keap1 by siKEAP1 is counteracted by increasing Nrf2 concentrations, which subsequently upregulate Keap1 and Srxn1 mRNA production (Fig 3C)
Os estudos revisados apontaram que o composto estimula a sntese de colgeno e de componentes importantes da matriz extracelular da pele, alm de modular enzimas relacionadas ao remodelamento cutneo durante a cicatrizao
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