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Regulation of xenobiotic-metabolizing enzymes by 5-demethylnobiletin and nobiletin to mitigate benzo[a]pyrene-induced DNA damage in vitro and in vivo
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4 PAG-sensitivity of CSSC utilization in cultured primary hepatocytes
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For RTHP2, the K63W mutation may stack with the benzyl moiety of R -THP to enforce selectivity, while the nearby L66A and M70L mutations may fine-tune pocket sterics
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