The SURMOUNT-1 trial showed that FDA-approved tirzepatide produced average weight loss of 15% at 5mg, 19.5% at 10mg, and 20.9% at 15mg over 72 weeks
People who eat quickly, have had general anesthesia, have trouble swallowing or coughing, are 65 and older, have a weakened immune system, use feeding tubes, have had a stroke, drink large amounts of alcohol and are unable to chew properly are the most at risk for aspiration and aspiration pneumonia
Patients receiving L-carnitne showed significant improvement compared to the placebo group
The enrollment period lasted from August 30, 2019, to March 20, 2020, and follow-up was completed on January 13, 2021.The participants were divided into four groups in a 1:1:1:1 ratio
According to the article, the difference is the pace and the checkpoints, not the drug