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In clinical trials comparing Synvisc to saline, patients treated with Synvisc experienced an average reduction in weight-bearing pain of 48.8%, compared to 25% for those treated with saline
However, the body weight of 5A-1MQ-treated obese mice (WD/LD-T group), which was indistinguishable from the other DIO groups at study start, was indistinguishable from the lean control (LD/LD-V) group at study completion (results with FDR correction
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doi:10.1155/2018/2414609
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