Published: Aug 7, 2025 Written by Klarity Editorial Team Published: Aug 7, 2025 Starting a GLP-1 medication like semaglutide (Ozempic or Wegovy) comes with certain expectations, particularly around appetite suppression
Insulin resistance is the hallmark of metabolic syndrome an increasingly common disorder diagnosed by the presence of three of five metabolic abnormalities: high blood pressure, elevated fasting triglycerides, low levels of beneficial HDL cholesterol, increased abdominal circumference, and high fasting blood glucose (Bassi 2014
That is why nutrient-dense meals and targeted supplementation can be helpful
One review found that GLP-1 agonists promote weight loss and improve blood pressure and blood lipid levels, which has a positive impact on cardiovascular risk factors
Many candidates also experience persistent cravings, insulin resistance, or metabolic slowing, which may be addressed by GLP-1 therapy