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It's also worth recognizing that this is quite rare
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10 These drug-related symptoms may be misdiagnosed as a new medical condition (i.e., PD) and the patient may be started on antiparkinsonian therapy, thus becoming vulnerable to additional adverse effects (e.g., delirium, hypotension)
Phase 1b/2a Subcutaneous Formulation (Obesity) Published: The Lancet, June 2025 Participants: 125 adults with overweight or obesity (BMI 27.039.9), aged 1855 Duration: Up to 36 weeks Dosing: Once-weekly subcutaneous amycretin, up to 60 mg Results: - Up to 22% absolute weight loss at 36 weeks (highest dose group) - Placebo-adjusted difference: approximately 24% - No weight-loss plateau observed at study end Safety: 81% of the 89 participants who reported a TEAE had gastrointestinal events
The genetics of mammalian circadian order and disorder: implications for physiology and disease
