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As a drug, it gained infamy as a Tour de France performance enhancer
Neuromolecular medicine, 7(1-2), 336
In a 2-year trial, acute pancreatitis was reported in 8 semaglutide-treated patients (0.27 cases per 100 patient-years) and 10 placebo-treated patients (0.33 cases per 100 patient-years), both on a background of standard of care.1 In trials of patients receiving oral semaglutide, pancreatitis was reported as a serious adverse event in 6 patients (0.1 events per 100 patient-years) receiving semaglutide versus 1 in comparator-treated patients (less than 0.1 events per 100 patient-years)
Tirzepatide accounts for fewer nerve-sensitivity reports than semaglutide, but no incidence has been established
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