Potentially, but only under medical supervision
How these numbers were derived: The percentages above come from the standard pharmacokinetic exponential accumulation model applied to retatrutide's confirmed approximately 6-day half-life (Jastreboff et al., NEJM 2023)
Interestingly, research shows that women may be twice as likely as men to experience side effects from GLP-1 medications
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Given the altered anatomy after gastric sleeve surgery and the potential for increased gastrointestinal side effects, extra caution and ongoing monitoring are essential