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Research has demonstrated involvement of the NO system, growth factor modulation (including VEGF, EGF), and FAK-paxillin signaling pathways
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The result: severe water retention, numbness and tingling in the hands (carpal tunnel symptoms from excessive GH), facial flushing, and paradoxically reduced GH output as the pituitary downregulates its response
Two versions: food present (valve partially closed) vs empty stomach (valve open)
The treatment also increased the ratio of whole-body lean mass to body weight by 6.4%
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