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It just showed that SULT1E1 was likely involved and that combinations of SULT variants plus GST variants were likely deleterious.[ref] Another cell line genome-wide study found more than 22 genes related to susceptibility to acetaminophen-induced liver damage

H., Yang, J

G., Reichelt, M., Gershenzon, J

Chronic exposure has been associated with: Liver stress Immune suppression Increased inflammatory burden (14) Trichothecenes Often associated with Stachybotrys chartarum , trichothecenes can: Inhibit protein synthesis Disrupt mucosal immunity Intensify inflammatory signaling (15) Gliotoxin Produced by certain Aspergillus species, gliotoxin has immunosuppressive effects and may impair macrophage function and immune clearance (16)

coli , such as cystathionine -lyase (CBL, encoded by metC )