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10.1242/dev.062554 74 MillerJ
Adipose-tissue gene expression laboratory studies have profiled changes in genes associated with lipolysis, -oxidation and adipogenesis following AOD-9604 exposure
(Arumugasaamy et al., 2019) found that both fluoxetine and sertraline slowed calcium oscillations in cardiomyocytes, inducing the increased secretion of troponin T and creatine kinase-MB, while also decreasing the secretion of N-terminal prohormone of brain natriuretic peptide (NT-proBNP), all three of which are key biomarkers of cardiac injury
Although this study has systematically elucidated the therapeutic efficacy and mechanisms of GPS in various diseases, its clinical translation still faces significant challenges
The increase of plasma long-chain ACs indicated that the fatty acid oxidation of depressed rats was incomplete, which may lead to a decrease in activities ( Table 1 Main information of pre-clinical researches studying the correlation between carnitine level and depression in animal
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