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Despite the prolonged exposure to high-fat diet, VilCre control, Gcg RA Null and Gcg RA VilCre mice all showed improved oral glucose tolerance in response to vildagliptin (Fig
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This translocation is supported by Karyopherin 1 (importin 5), that functions as an adaptor molecule, and Karyopherin 1 (importin 1), the transport receptor that allows NRF2 translocation from the cytoplasm to the nuclear side of the NPC, due to Nuclear Localization Signal (NLS) sequences in NRF2 [160]
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