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The hormone leptin is fundamental in the regulation of body weight since it suppresses the orexigenic (appetite-inducing) pathway and activates the anorexigenic (satiety-inducing) pathway (8)
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Reduction of intestinal trimethylamine by probiotics ameliorated lipid metabolic disorders associated with atherosclerosis
Patients with established cardiovascular disease including previous myocardial infarction, stroke, or peripheral arterial diseaseare particularly suitable candidates, given the proven cardiovascular benefits of both drug classes
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