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Since D2HG and L2HG are indistinguishable in standard LC-MS, to determine which 2HG enantiomer(s) is affected, we adapted a chiral N-(p-toluenesulfonyl)-L-phenylalanyl chloride (TSPC) derivation followed by liquid chromatography with tandem mass spectrometry (LC-MS/MS) analysis 24,40
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The APX isoforms are stress sensitive and are regulated by nearly all kinds of abiotic and biotic stress conditions (Shigeoka et al., 2002)
Fundamentally, ozone should never be inhaled, as this can cause severe lung irritation and fluid buildup
Doctors often use Phentermine before resorting to surgical intervention, due to its proven safety and efficiency
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