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What your body does with them is not
Trends Endocrinol Metab 28 (5), 340353
In vitro assays using BaF-BO3 cells transfected with the hGH receptor confirmed that AOD9604 does not compete for the hGH receptor and does not induce cell proliferation unlike intact hGH establishing that it operates via a novel mechanism distinct from traditional hGH-stimulated pathways
This distinct mechanism makes 5-Amino-1MQ a useful research tool for examining enzymatic regulation of nicotinamide turnover, methylation pathway dynamics, enzyme-inhibitor interactions, and regulatory processes associated with NNMT activity
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