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Research on postmenopausal women with overweight/obesity have indicated that those who used GLP-1 RAs combined with HRT experienced greater total body weight loss compared to those using GLP-1 RAs alone, suggesting that restored estrogen levels may enhance the metabolic efficacy of the GLP-1 medications

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For those navigating this landscape, the key is making the best decision with the information and options available today, while staying informed about what is coming

Adipose tissue, particularly visceral fat, contributes to insulin resistance through the release of inflammatory mediators and free fatty acids