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For most people, these settle as the body adjusts, without needing to stop treatment

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The semaglutide mixing chart for 5mg explores these tradeoffs in more detail

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In the Phase 3 ATTAIN-1 trial, adults with obesity taking the highest approved dose achieved an average weight loss of 12.4% at 72 weeks compared with approximately 0.9% with placebo

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In the USA, dedicated resources, including strategies focused on diverse recruitment and retention and outreach efforts, are being implemented to include participants from ethnic and racial minorities, as well as those from different socioeconomic backgrounds, who are usually underrepresented in AD clinical trials [67]

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