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SADEGHI, H., MANSOURIAN, M., PANAHIKOKHDAN, E., SALEHPOUR, Z., SADATI, I., ABBASZADEH-GOUDARZI, K., ASFARAM, A

Tesamorelin adds a targeted intervention

Mechanistically, inactivation of the CD73/adenosine A2A receptor (A2AR) signaling cascade accelerated the de novo synthesis and consumption of GSH with GSSG accumulation and concomitant mitochondrial lipid peroxidation, which linked potentially to PKA/E2F1dependent fine-tuning of the ratio of GSR to GPX4

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